Huntington disease patients and transgenic mice have similar pro-catabolic serum metabolite profiles
نویسندگان
چکیده
منابع مشابه
Huntington disease patients and transgenic mice have similar pro-catabolic serum metabolite profiles.
There has been considerable progress recently towards developing therapeutic strategies for Huntington's disease (HD), with several compounds showing beneficial effects in transgenic mouse models. However, human trials in HD are difficult, costly and time-consuming due to the slow disease course, insidious onset and patient-to-patient variability. Identification of molecular biomarkers associat...
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ژورنال
عنوان ژورنال: Brain
سال: 2006
ISSN: 1460-2156,0006-8950
DOI: 10.1093/brain/awl027